Potent allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50
= 31 nM). Inhibits PRMT3-mediated methyltransferase activity in vitro
. Displays >100-fold selectivity against 31 other methyltransferases and 250 other non-epigenetic targets.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the SGC 707 probe summary
on the SGC website.
Other Product-Specific Information:
A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3).
Kaniskan et al.