SHIP 2a

Key Product Details

Product Description

SHIP 2a is a cystathione γ lyase (CSE) inhibitor (IC₅₀ = 6.3 μM). Inhibits H₂S production in mouse aorta homogenates and L-cysteine-induced relaxation of rat aortic rings ex vivo.

Product Specifications for SHIP 2a

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for SHIP 2a

The following data is based on the product molecular weight 184.22.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.43 mL	27.14 mL	54.28 mL
5 mM	1.09 mL	5.43 mL	10.86 mL
10 mM	0.54 mL	2.71 mL	5.43 mL
50 mM	0.11 mL	0.54 mL	1.09 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Corvino Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production. Sci.Rep. 2016 PMID:  27708394

Product Documents for SHIP 2a