SIAH3 Antibody - BSA Free

Western Blot: SIAH3 Antibody [NBP2-83524]

Western Blot: SIAH3 Antibody [NBP2-83524] - Host: Rabbit. Target Name: SIAH3. Sample Type: MCF7 Whole Cell lysates. Antibody Dilution: 1.0ug/ml

Western Blot: SIAH3 Antibody - BSA Free [NBP2-83524] -

Melatonin injection ameliorates fibrotic CKD and improves kidney function in a CKD mouse model via miR-4516/SIAH3/PINK1 pathway. (A) miR-4516 expression level in renal cortex of healthy kidney control and CKD mice either treated with melatonin, or both melatonin and miR-4516 inhibitor, measured by qRT-PCR (n = 3). (B) Expression of SIAH3 and PINK1 in renal cortex of each groups. Protein expression level was quantified by densitometry and normalized to alpha -tubulin levels (n = 3). (C) IHC staining for SIAH3 in renal cortex of each mouse group. (D) H&E staining of renal cortex of each mouse group. (E,F) Measurement of blood urea nitrogen (E) and creatinine (F) level in serum of each mouse group (n = 5). The values represent mean +/- SEM, * p < 0.05, ** p < 0.01 versus healthy kidney control; #p < 0.05, ##p < 0.01 versus PBS; $p < 0.05, $$p < 0.01 versus melatonin. The alpha -tubulin was used as Western blot loading control for whole tissue lysates. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/34359852), licensed under a CC-BY license. Not internally tested by Novus Biologicals.