Chemical Name: 1-(4-Chlorophenyl)-N,N-dimethyl-α-(2-methylpropyl)cyclobutanemethanamine hydrochloride
Biological Activity5-HT and noradrenalin re-uptake inhibitor (SNRI). Produces weight loss in rats via inhibition of food intake and increased energy expenditure. Antidepressant.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat.
Jackson et al.
In vivo criteria to differentiate monoamine reuptake inhibitors from releasing agents: sibutramine is a reuptake inhibitor.
Gundlah et al.
The pharmacology of sibutramine hydrochloride (BTS 54524), a new antidepressant which induces rapid noradrenergic down-regulation.
Buckett et al.
Citation for Sibutramine hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Sibutramine hydrochloride include:
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