SID 7969543

Key Product Details

Product Description

SID 7969543 is a selective steroidogenic factor-1 (SF-1, NR5A1) inhibitor (IC₅₀ values are 0.76, >33 and >33 μM at SF-1, RORα and VP16 respectively). Inhibits SF-1-dependent luciferase expression in HEK 293T cells in vitro (IC₅₀ = 30 nM).

Product Specifications for SID 7969543

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for SID 7969543

The following data is based on the product molecular weight 452.46.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.21 mL	11.05 mL	22.10 mL
5 mM	0.44 mL	2.21 mL	4.42 mL
10 mM	0.22 mL	1.11 mL	2.21 mL
50 mM	0.04 mL	0.22 mL	0.44 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

• Madoux Potent, selective and cell penetrant inhibitors of SF-1 by functional ultra-high-throughput screening. Mol.Pharmacol. 2008 PMID: 18334597
• Roth Synthesis of small molecule inhibitors of the orphan nuclear receptor steroidogenic factor-1 (NR5A1) based on isoquinolinone scaffolds. Bioorg.med.Chem.Lett. 2008 PMID: 18374567

Product Documents for SID 7969543