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SID 7969543

3440 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3440/10
3440/50
SID 7969543 | CAS No. 868224-64-0 | Nuclear Receptor Antagonists
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Description: Selective steroidogenic factor-1 (SF-1, NR5A1) inhibitor

Chemical Name: Ethyl 2-[[2-[2-[(2,3-Dihydro-1,4-benzodioxin-6-yl)amino]-2-oxoethyl]-1,2-dihydro-1-oxo-5-isoquinolinyl]oxy]propanoate

Purity: ≥98%

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Biological Activity

Selective steroidogenic factor-1 (SF-1, NR5A1) inhibitor (IC50 values are 0.76, >33 and >33 μM at SF-1, RORα and VP16 respectively). Inhibits SF-1-dependent luciferase expression in HEK 293T cells in vitro (IC50 = 30 nM).

Technical Data

M.Wt:
452.46
Formula:
C24H24N2O7
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
868224-64-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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