Recombinant Human SIL1 His Protein

Novus Biologicals | Catalog # NBP1-98949

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
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Product Specifications

Description

A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 32-461 of Human SIL1

Source: E.coli

Amino Acid Sequence: MHQNLKEFAL TNPEKSSTKE TERKETKAEE ELDAEVLEVF HPTHEWQALQ PGQAVPAGSH VRLNLQTGER EAKLQYEDKF RNNLKGKRLD INTNTYTSQD LKSALAKFKE GAEMESSKED KARQAEVKRL FRPIEELKKD FDELNVVIET DMQIMVRLIN KFNSSSSSLE EKIAALFDLE YYVHQMDNAQ DLLSFGGLQV VINGLNSTEP LVKEYAAFVL GAAFSSNPKV QVEAIEGGAL QKLLVILATE QPLTAKKKVL FALCSLLRHF PYAQRQFLKL GGLQVLRTLV QEKGTEVLAV RVVTLLYDLV TEKMFAEEEA ELTQEMSPEK LQQYRQVHLL PGLWEQGWCE ITAHLLALPE HDAREKVLQT LGVLLTTCRD RYRQDPQLGR TLASLQAEYQ VLASLELQDG EDEGYFQELL GSVNSLLKEL RLEHHHHHH

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human SIL1 His Protein

SDS-PAGE: Recombinant Human SIL1 His Protein [NBP1-98949]

SDS-PAGE: Recombinant Human SIL1 His Protein [NBP1-98949]

SDS-Page: Recombinant Human SIL1 Protein [NBP1-98949] - 15% SDS-PAGE (3ug)

Formulation, Preparation, and Storage

NBP1-98949
Formulation 20 mM Tris-HCl buffer (pH 8.0), 0.1 M NaCl, 10% glycerol
Preservative No Preservative
Concentration 0.5 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SIL1

Nucleotide exchange factor, also known as SIL1, is a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Recombinant human SIL1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

BAPMarinesco-Sjogren syndrome, BiP-associated protein, MSS, nucleotide exchange factor SIL1, SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae), ULG5

Gene Symbol

SIL1

Additional SIL1 Products

Product Documents for Recombinant Human SIL1 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human SIL1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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