Amyloid Precursor Protein (APP) is a type I transmembrane protein that is ubiquitously expressed on cell surfaces. It undergoes complex proteolytic processing and is cleaved by alpha-, beta-, and gamma-Secretases to generate soluble APP alpha, soluble APP beta, and Amyloid beta (A beta) fragments of several lengths. One of these fragments, A beta 42, generated by beta- and gamma-Secretase activities, has been implicated in Alzheimer's disease. Aberrantly high levels of this peptide form and accumulate in the brains of Alzheimer's disease patients to create the senile plaques characteristic of the disease.
Simple Plex Control for Human Amyloid Beta aa1-40
R&D Systems | Catalog # 897033
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Product Summary for Simple Plex Control for Human Amyloid Beta aa1-40
Formulation, Preparation, and Storage
Shipping
Storage
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: Amyloid beta
Alternate Names
Gene Symbol
Additional Amyloid beta Products
Product Documents for Simple Plex Control for Human Amyloid Beta aa1-40
Certificate of Analysis
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Product Specific Notices for Simple Plex Control for Human Amyloid Beta aa1-40
For research use only
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