Vascular endothelial growth factor D (VEGF-D) is a homodimeric ligand of VEGF R3/Flt-4 and is synthesized with N- and C-terminal propeptides. Fully processed VEGF-D containing only the VEGF homology domain can additionally bind and activate VEGF R2/KDR/Flk-1. VEGF-D is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. VEGF R3 is strongly expressed in lymphatic endothelial cells and is essential for regulation of the growth and differentiation of lymphatic endothelium. While VEGF-C is the critical ligand for VEGF R3 during embryonic lymphatic development, while VEGF-D is most active in neonatal lymphatic maturation and bone growth.
Simple Plex Control for Human VEGF-D
R&D Systems | Catalog # 897118
Control for use with Human VEGF-D Simple Plex Assay Cartridge Kit
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Key Product Details
Species
Human
Applications
Simple Plex Automated Immunoassay
Product Summary for Simple Plex Control for Human VEGF-D
INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human VEGF-D concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.
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Formulation, Preparation, and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: VEGF-D
Long Name
Vascular Endothelial Growth Factor D/cFos-induced Growth Factor
Alternate Names
FIGF, VEGFD
Gene Symbol
VEGFD
Additional VEGF-D Products
Product Documents for Simple Plex Control for Human VEGF-D
Certificate of Analysis
To download a Certificate of Analysis, please enter your Simple Plex catalog number and lot number in the search boxes below.
Product Specific Notices for Simple Plex Control for Human VEGF-D
For research use only
Citations for Simple Plex Control for Human VEGF-D
View all citations for the Simple Plex platform on Bio-Techne.com.
Please visit our Instrument Citation Database on Bio-Techne.com to search our collection of scientific articles that feature our instruments.
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