Simple Plex Human Axl Cartridge
R&D Systems | Catalog # SPCKB-PS-000472
Customize This Cartridge
Simple Plex cartridges are custom built to fit your needs. Choose from over 350 assays spanning human, mouse, rat, and non-human primate. Just select your sample type, cartridge size (16, 32, or 72 samples), and up to 8 analytes per cartridge. Customize this cartridge.
Key Product Details
Assay Length
Sample Type & Volume Required Per Well*
Sensitivity
Assay Range
Simple Plex Human Axl Cartridge Summary
*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay's minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.
Compatible Instruments
Ella Automated Immunoassay System
Product Specifications
Assay Type
Format
Species
Specificity
Cross-reactivity
Interference
Precision
Intra-Assay Precision (Precision within an assay) Each control was tested multiple times in one Axl assay.
Inter-Assay Precision (Precision between assays) Replicates of each Axl control were tested in multiple assays performed by at least three technicians using two lots of reagents for human Axl.
EDTA Plasma, Heparin Plasma, Serum
| Intra-Assay Precision | Inter-Assay Precision | |||
|---|---|---|---|---|
| Sample | 1 | 2 | 1 | 2 |
| n | 16 | 16 | 23 | 25 |
| Mean (pg/mL) | 420 | 19,305 | 383 | 19,730 |
| Standard Deviation | 16.3 | 1708 | 26.4 | 1794 |
| CV% | 3.9 | 8.8 | 6.9 | 9.1 |
Recovery for Simple Plex Human Axl Cartridge
Recovery was not necessary as human Axl shows 5 points of natural linearity.
Linearity
Samples containing and/or spiked with high concentrations of human Axl were serially diluted with Sample Diluent to produce samples within the dynamic range of the assay
Scientific Data Images for Simple Plex Human Axl Cartridge
Simple Plex Human Axl Assay Standard Curve
Data shown represents typical performance results for Lower Limit of Quantitation (LLOQ) and Upper Limit of Quantitation (ULOQ) for Simple Plex Human Axl Assay. Assay range is 48.72-74,340 pg/mL.Preparation and Storage
Shipping
Stability & Storage
Background: Axl
Axl, also known as Ufo and Ark, is a widely expressed glycoprotein in the TAM receptor tyrosine kinase family. TAM family receptors (Dtk/Tyro3, Axl, and Mer) are involved in regulation of the inflammatory response, cell survival and migration, and tumorigenesis. Axl binds the vitamin K-dependent protein Gas6, triggering platelet aggregation and thrombus formation, macrophage and dendritic cell phagocytosis of apoptotic cells, NK cell development from hematopoietic progenitor cells, and in vivo angiogenesis. Axl is highly expressed in solid cancers and promotes in vivo tumorigenesis and tumor cell invasiveness. It contributes to vascular remodeling and inflammatory cell infiltration in response to hypertension and restricted blood flow. It also functions as a cellular entry receptor for Gas6-opsonized lentiviruses.
Long Name
Alternate Names
Gene Symbol
Additional Axl Products
Product Documents for Simple Plex Human Axl Cartridge
Certificate of Analysis
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Product Specific Notices for Simple Plex Human Axl Cartridge
For research use only
Related Research Areas
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