Simple Plex Human Cystatin C Cartridge

Catalog #: SPCKB-PS-007569 Datasheet / COA / SDS
Simple Plex Human Cystatin C assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer
Catalog # Availability Size / Price Qty
SPCKB-PS-007569
SPCKC-PS-007569
SPCKA-PS-007569
Human Cystatin C Simple Plex Assay Standard Curve
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Simple Plex Human Cystatin C Cartridge Summary

Specificity
Natural and recombinant human Cystatin C
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.Cross-species reactivity observed with 1 or more species tested.
Interference
No significant interference observed with available related molecules.

*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay’s minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.

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Product Summary

Simple Plex assay for the detection of human Cystatin C in cell culture supernatant (CCS), serum, plasma (EDTA/Heparin), saliva, urine, and cerebrospinal fluid (CSF)

Recovery

Recovery at three different spiked concentrations within the range of the assay was evaluated.

Linearity

Samples containing and/or spiked with high concentrations of human Cystatin C were serially diluted with Sample Diluent to produce samples within the dynamic range of the assay.
Human Cystatin C Simple Plex Assay Linearity

Scientific Data

Human Cystatin C Simple Plex Assay Standard Curve

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Preparation and Storage

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: Cystatin C

Cystatin C is a secreted cysteine protease inhibitor that inhibits Cathepsins B, H, K, L, and S. Cystatin C serum concentration correlates closely to the glomerular filtration rate (GFR); elevated levels are associated with coronary artery and cardiovascular disease risk. Dysregulation of Cystatin C can modulate tumor growth and metastasis. In humans, the L68Q variant forms dimers and oligomers more easily than wild type protein and is the cause for hereditary Cystatin C amyloid angiopathy.

Entrez Gene IDs:
1471 (Human); 13010 (Mouse); 25307 (Rat)
Alternate Names:
ARMD11; bA218C14.4 (cystatin C); CST3; cystatin 3; cystatin C (amyloid angiopathy and cerebral hemorrhage); Cystatin C; cystatin-3; cystatin-C; Gamma-trace; MGC117328; Neuroendocrine basic polypeptide; Post-gamma-globulin

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