Simple Plex Human Gas6 Cartridge
R&D Systems | Catalog # SPCKB-PS-000491
Customize This Cartridge
Simple Plex cartridges are custom built to fit your needs. Choose from over 350 assays spanning human, mouse, rat, and non-human primate. Just select your sample type, cartridge size (16, 32, or 72 samples), and up to 8 analytes per cartridge. Customize this cartridge.
Key Product Details
Assay Length
Sample Type & Volume Required Per Well*
Sensitivity
Assay Range
Simple Plex Human Gas6 Cartridge Summary
*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay's minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.
Compatible Instruments
Ella Automated Immunoassay System
Product Specifications
Assay Type
Format
Species
Specificity
Cross-reactivity
Interference
Precision
Intra-Assay Precision (Precision within an assay) Each control was tested multiple times in one Gas6 assay.
Inter-Assay Precision (Precision between assays) Replicates of each Gas6 control were tested in multiple assays performed by at least three technicians using two lots of reagents for human Gas6.
EDTA Plasma, Heparin Plasma, Serum
| Intra-Assay Precision | Inter-Assay Precision | |||
|---|---|---|---|---|
| Sample | 1 | 2 | 1 | 2 |
| n | 16 | 16 | 21 | 20 |
| Mean (pg/mL) | 55.6 | 2933 | 53.6 | 2787 |
| Standard Deviation | 3.31 | 201 | 3.18 | 184 |
| CV% | 5.9 | 6.9 | 5.9 | 6.6 |
Recovery for Simple Plex Human Gas6 Cartridge
Recovery was not necessary as human Gas6 shows 5 points of natural linearity.
Linearity
Samples containing and/or spiked with high concentrations of human Gas6 were serially diluted with Sample Diluent to produce samples within the dynamic range of the assay
Scientific Data Images for Simple Plex Human Gas6 Cartridge
Simple Plex Human Gas6 Assay Standard Curve
Data shown represents typical performance results for Lower Limit of Quantitation (LLOQ) and Upper Limit of Quantitation (ULOQ) for Simple Plex Human Gas6 Assay. Assay range is 2.62-10,000 pg/mL.Preparation and Storage
Shipping
Stability & Storage
Background: Gas6
Gas6 (Growth Arrest Specific 6) is a secreted protein that contains an extensively gamma-carboxylated N-terminal Gla domain and is dependent upon vitamin K for activity. Gas6 signals through the receptors Axl, Dtk/Tyro3, and Mer and is inhibited by shed soluble forms of Axl and Mer. Gas6 protects cells from stress-induced apoptosis and promotes phagocytosis of apoptotic cell debris, promotes platelet activation but inhibits inflammatory cytokine production, and inhibits VEGF-induced angiogenesis, and regulates tumor cell invasiveness.
Long Name
Alternate Names
Gene Symbol
Additional Gas6 Products
Product Documents for Simple Plex Human Gas6 Cartridge
Certificate of Analysis
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Product Specific Notices for Simple Plex Human Gas6 Cartridge
For research use only
Related Research Areas
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