Simple Plex Human Mesothelin Cartridge
Simple Plex Human Mesothelin Cartridge Summary
*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay’s minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.
Product Summary
Precision
Serum, EDTA Plasma, Heparin Plasma
Intra-Assay Precision | Inter-Assay Precision | |||
---|---|---|---|---|
Sample | 1 | 2 | 1 | 2 |
n | 16 | 16 | 22 | 19 |
Mean (pg/mL) | 299 | 14366 | 296 | 14297 |
Standard Deviation | 10 | 615 | 14.5 | 792 |
CV% | 3.3 | 4.3 | 4.9 | 5.5 |
Recovery
Recovery was not necessary as Mesothelin shows natural linearity data from a neat sample to a 1:16 dilution.
Linearity
Scientific Data
Product Datasheets
Preparation and Storage
Background: Mesothelin
Mesothelin, also known as CAK1 and ERC, is derived from a precursor that also includes Megakaryocyte Potentiating Factor (MPF). Following cleavage of the precursor, Mesothelin remains attached to the cell surface via a GPI linkage. Mesothelin is normally expressed on mesothelial cells in the pleura, pericardium, and peritoneum as well as in the developing and postnatal pancreas. It is upregulated in mesotheliomas and a range of carcinomas and adenomas. Mesothelin promotes tumor cell proliferation, migration, anchorage-independent growth, and tumor progression.
FAQs
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