SKF 38393 hydrobromide

  ( 15 citations )    
Product Datasheet
Catalog Number:0922
Chemical Name:(±)-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrobromide
Product Details
Citations (15)
Supplemental Products
Reviews
Biological Activity
Prototypical D1-like dopamine receptor selective partial agonist (Ki values are 1, ~ 0.5, ~ 150, ~ 5000 and ~ 1000 nM for D1, D5, D2, D3 and D4 receptors respectively).
Technical Data
  • M.Wt:
    336.23
  • Formula:
    C16H17NO2.HBr
  • Solubility:
    Soluble to 25 mM in water with gentle warming and to 25 mM in ethanol with gentle warming
  • Purity:
    >99
  • Storage:
    Desiccate at -20°C
  • CAS No:
    20012-10-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for SKF 38393 hydrobromide include:

15 Citations: Showing 1 - 10
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  1. Levo-Tetrahydroberberrubine Produces Anxiolytic-Like Effects in Mice through the 5-HT 1A Receptor.
    Authors: Mi
    Plos One  2017;12:e0168964
  2. OCD candidate gene SLC1A1/EAAT3 impacts basal ganglia-mediated activity and stereotypic behavior.
    Authors: Zike
    Proc Natl Acad Sci USA  2017;114(22):5719
  3. Dopamine D1 receptor activation regulates the expression of the estrogen synthesis gene aromatase B in radial glial cells.
    Authors: Xing Et al.
    Eur J Neurosci  2015;9:310
  4. Endogenous 17β-estradiol is required for activity-dependent long-term potentiation in the striatum: interaction with the dopaminergic system.
    Authors: Tozzi Et al.
    Front Cell Neurosci  2015;9:192
  5. Dopamine Modulates the Activity of Sensory Hair Cells.
    Authors: Toro Et al.
    J Neurosci  2015;35:16494
  6. Selective Effects of PDE10A Inhibitors on Striatopallidal Neurons Require Phosphatase Inhibition by DARPP-32(1,2,3).
    Authors: Polito Et al.
    J Immunol  2015;2
  7. Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: σ1-D1-H3 receptor complexes as key targets for reducing cocaine's effects.
    Authors: Moreno Et al.
    J Neurosci  2014;34:3545
  8. Dopaminergic modulation of GABAergic transmission in the entorhinal cortex: concerted roles of α1 adrenoreceptors, inward rectifier K+, and T-type Ca2+ channels.
    Authors: Cilz Et al.
    Cereb Cortex  2014;24:3195
  9. Diminished FoxP2 levels affect dopaminergic modulation of corticostriatal signaling important to song variability.
    Authors: Murugan Et al.
    Neuron  2013;80:1464
  10. Age-dependent regulation of synaptic connections by dopamine D2 receptors.
    Authors: Jia Et al.
    Nat Neurosci  2013;16:1627
  11. Dopaminergic modulation of ganglion-cell photoreceptors in rat.
    Authors: Hook Et al.
    Eneuro  2012;35:507
  12. D4 dopamine receptors modulate NR2B NMDA receptors and LTP in stratum oriens of hippocampal CA1.
    Authors: Herwerth Et al.
    Cereb Cortex  2012;22:1786
  13. Stimulation of dopamine receptor D5 expressed on dendritic cells potentiates Th17-mediated immunity.
    Authors: Prado Et al.
    J Biol Chem  2012;188:3062
  14. Dopaminergic regulation of sleep and cataplexy in a murine model of narcolepsy.
    Authors: Burgess Et al.
    Sleep  2010;33:1295
  15. Identification of dopamine D1-D3 receptor heteromers. Indications for a role of synergistic D1-D3 receptor interactions in the striatum.
    Authors: Marcellino Et al.
    Front Neurosci  2008;283:26016
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