SKF 82958 hydrobromide

Catalog # Availability Size / Price Qty
5719/10
5719/50
Cat.No. 5719 - SKF 82958 hydrobromide | C19H20ClNO2.HBr | CAS No. 74115-01-8
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Description: D1 agonist

Chemical Name: 6-Chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-1H-3-benzazepine-7,8-diol hydrobromide

Purity: ≥98%

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Biological Activity

D1 agonist. Increases renal blood flow in animal models and promotes contralateral rotation in rats with unilateral lesions of the substantia nigra. Also augments GABAB inhibitory post-synaptic potentials (ipsp) in ventral tegmental area in brain slices.

Technical Data

M.Wt:
410.73
Formula:
C19H20ClNO2.HBr
Solubility:
Soluble to 100 mM in DMSO and to 5 mM in water with gentle warming
Purity:
≥98%
Storage:
Store at RT
CAS No:
74115-01-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Dopaminergic activity of substituted 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines.
    Pfeiffer et al.
    J.Med.Chem., 1982;25:352
  2. Dopamine D1 receptors facilitate transmitter release.
    Cameron and Williams
    Nature, 1993;366:344

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