SKF 83822 hydrobromide

Catalog # Availability Size / Price Qty
2075/10
2075/50
SKF 83822 hydrobromide | CAS No. 74115-10-9 | Dopamine D1 and D5 Receptor Agonists
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Description: Selective D1-like agonist

Chemical Name: 6-Chloro-2,3,4,5-tetrahydro-1-(3-methylphenyl)-3-(2-propenyl)-1H-3-benzazepine-7,8-diol hydrobromide

Purity: ≥98%

Product Details
Citations (3)
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Biological Activity

High affinity, selective dopamine D1-like receptor agonist. Ki values are 3.2, 3.1, 186, 66, 335, 1167, 1251 and 1385 nM at recombinant D1, D5, D2, D3, D4, 5-HT2A, α1A and α1B receptors respectively. Stimulates adenylyl cyclase (EC50 = 65 nM) but not phosphoinositide hydrolysis. Induces extreme arousal and hyperlocomotion following subcutaneous administration in monkeys.

Technical Data

M.Wt:
424.76
Formula:
C20H22ClNO2.HBr
Solubility:
Soluble to 10 mM in ethanol and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
74115-10-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for SKF 83822 hydrobromide

The citations listed below are publications that use Tocris products. Selected citations for SKF 83822 hydrobromide include:

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