SLV 320

  ( 1 citations ) ( 1 Review )    
Product Datasheet
Catalog Number:3344
Chemical Name:trans-4-[(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol
Product Details
Citations (1)
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Reviews
Biological Activity
Potent and selective adenosine A1 receptor antagonist (Ki values are 1, 200, 398 and 3981 nM at human A1, A3, A2A and A2B receptors respectively). Suppresses cardiac fibrosis and attenuates albuminuria, without effect on blood pressure in animal models of chronic renal failure. Orally active.
Technical Data
  • M.Wt:
    308.38
  • Formula:
    C18H20N4O
  • Solubility:
    Soluble to 100 mM in DMSO and to 50 mM in ethanol
  • Purity:
    >99
  • Storage:
    Store at -20°C
  • CAS No:
    251945-92-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for SLV 320 include:

1 Citations: Showing 1 - 1

  1. Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbarmuscular atrophy.
    Authors: Badders
    Nat Med  2018;24(4):424

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VersaClone cDNA Plasmids
Description Application Cat# Citations Images  

Mouse Adenosine A1 R (NP_000665) VersaClone cDNA

RDC2041
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Human Adenosine A1 R (NP_000665) VersaClone cDNA

RDC0213
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Average Rating: 5 (Based on 1 review)

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  Other Hitesh Soni 01/04/2018
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Species Other
Pub Med ID 28855189

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Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

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