SM-21 maleate

  ( 2 citations )    
Product Datasheet
Catalog Number:0751
Chemical Name:(±)-Tropanyl 2-(4-chlorophenoxy)butanoate maleate
Product Details
Citations (2)
Reviews
Biological Activity
Potent and selective σ2 antagonist with central effects following systemic administration. Causes increased release of acetylcholine at central muscarinic synapses. Potent analgesic (efficacy comparable to morphine) and nootropic agent.
Technical Data
  • M.Wt:
    453.92
  • Formula:
    C18H24ClNO3.C4H4O4
  • Solubility:
    Soluble to 25 mM in water
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    155059-42-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for SM-21 maleate include:

2 Citations: Showing 1 - 2
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  1. Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by ifenprodil: the role of σ-1 and IP3 receptors.
    Authors: Ishima and Hashimoto
    J Diabetes Res  2012;7:e37989
  2. Effects of UMB24 and (+/-)-SM 21, putative σ2-preferring antagonists, on behavioral toxic and stimulant effects of cocaine in mice.
    Authors: Matsumoto Et al.
    PLoS One  2007;86:86

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