SMAC/Diablo Antibody Blocking Peptide

Name: SMAC/Diablo Antibody Blocking Peptide
Brand: Novus Biologicals
SKU: NBP1-76772PEP
Price: 169 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-76772PEP

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Product Documents

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Source

Synthetic

Applications

Antibody Competition

View all SMAC/Diablo Proteins and Enzymes »

Product Specifications

Description

A blocking peptide containing 16 amino acids near the carboxy terminus of mouse SMAC/Diablo.

Source: Synthetic

(Accession #: AF203914)

Application Notes

This peptide is useful as a blocking peptide for NBP1-76772.

For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Scientific Data Images for SMAC/Diablo Antibody Blocking Peptide

Western Blot: SMAC/Diablo Antibody Blocking Peptide [NBP1-76772PEP]

Western Blot: Smac Peptide [NBP1-76772PEP] - blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37C

Formulation, Preparation, and Storage

NBP1-76772PEP

Formulation	PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative	0.02% Sodium Azide
Concentration	0.2 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20C. Avoid freeze-thaw cycles.

Background: SMAC/Diablo

Smac/DIABLO is a mitochondrial protein which activates various forms of apoptosis. Specifically, Smac exits the mitochondria and enters the cytosol where it initiates apoptosis by neutralizing members of the IAP family of apoptosis inhibitory proteins. Mitochondrial-mediated apoptosis is important in animal development and tissue homeostasis, with alterations resulting in a range of malignant disorders. Upon apoptotic stimuli, the mitochondrial proteins cytochrome c and Smac/DIABLO are released into the cytosol. The release of these proteins, however, occurs via different mechanisms.

Long Name

Second Mitochondria-derived Activator of Caspase

Alternate Names

Diablo

Gene Symbol

DIABLO

Additional SMAC/Diablo Products

Product Documents for SMAC/Diablo Antibody Blocking Peptide

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Product Specific Notices for SMAC/Diablo Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

Bcl-2 Proteins and Regulators

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