SNAP
Tocris Bioscience | Catalog # 0598
Key Product Details
Description
Product Description
SNAP is a stable analog of endogenous S-nitroso compounds. A source of NO in vivo which unlike organic O-nitrates does not induce tolerance. Decomposes slowly in solution with a t½ of 37h.
Product Specifications for SNAP
Molecular Weight
Formula
Storage
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 22.02 | 100 |
Preparing Stock Solutions for SNAP
The following data is based on the product molecular weight 220.24.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.54 mL | 22.70 mL | 45.41 mL |
| 5 mM | 0.91 mL | 4.54 mL | 9.08 mL |
| 10 mM | 0.45 mL | 2.27 mL | 4.54 mL |
| 50 mM | 0.09 mL | 0.45 mL | 0.91 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 61 publications citing the usage of this product.
- Ferrero Comparative effects of several nitric oxide donors on intracellular cyclic GMP levels in bovine chromaffin cells: correlation with nitric oxide production. Br.J.Pharmacol. 1999 PMID: 10401570
- Cross Neurotoxicity in conscious rats following intraventricular SNAP, a nitric oxide donor. Neuropharmacology 1994 PMID: 7969812
- Ekblad and Sundler Motor responses in rat ileum evoked by nitric oxide donors vs. field stimulation: modulation by pituitary adenylate cyclase-activating peptide, forskolin and guanylate cyclase inhibitors. J.Pharmacol.Exp.Ther. 1997 PMID: 9336304
- Bauer and Fung Differential thermodynamic effects and tolerance properties of nitrogly. and S-nitrosothiol in experimental heart failure. J.Pharmacol.Exp.Ther. 1991 PMID: 1899118
Product Documents for SNAP
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for SNAP
For research use only
Citations for SNAP
Customer Reviews for SNAP (1)
Have you used SNAP?
Submit a review and receive an Amazon gift card!
$25/€18/£15/$25CAN/¥2500 Yen for a review with an image
$10/€7/£6/$10CAN/¥1110 Yen for a review without an image
Submit a review
Customer Images
-
Species: RatAssay Type: In VivoCell Line/Tissue: brainVerified Customer | Posted 03/18/2020IPSCs used before and 15 min after drug application (SNAP, 400 µM)
There are no reviews that match your criteria.