SNAP

Catalog # Availability Size / Price Qty
0598/10
0598/50
SNAP | CAS No. 79032-48-7 | Nitric Oxide Donor/Precursor Compounds
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Description: A stable analog of endogenous S-nitroso compounds

Chemical Name: (S)-Nitroso-N-acetylpenicillamine

Product Details
Citations (10)
Reviews

Biological Activity

SNAP is a stable analog of endogenous S-nitroso compounds. A source of NO in vivo which unlike organic O-nitrates does not induce tolerance. Decomposes slowly in solution with a t½ of 37h.

Technical Data

M.Wt:
220.24
Formula:
C7H12N2O4S
Solubility:
Soluble to 100 mM in DMSO
Storage:
Store at -20°C
CAS No:
79032-48-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for SNAP

The citations listed below are publications that use Tocris products. Selected citations for SNAP include:

10 Citations: Showing 1 - 10

  1. Constitutive activation of kappa opioid receptors at ventral tegmental area inhibitory synapsesfollowing acute stress
    Authors: Polter
    Elife  2017;6:e23786
  2. Endothelin-1 contributes to endothelial dysfunction and enhanced vasoconstriction through augmented superoxide production in penile arteries from Ins-resistant obese rats: role of ET(A) and ET(B) receptors.
    Authors: Sánchez Et al.
    Br J Pharmacol  2014;171:5682
  3. Biphasic effect of nitric oxide on the cardiac voltage-dependent anion channel.
    Authors: Cheng Et al.
    FEBS Lett  2011;585:328
  4. NO-released zinc supports the simultaneous binding of Raf-1 and PKCγ cysteine-rich domains to HINT1 protein at the mu-opioid receptor.
    Authors: Rodríguez-Muñoz Et al.
    Antioxid Redox Signal  2011;14:2413
  5. Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of Ins-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5 receptor-i
    Authors: Sunters Et al.
    J Biol Chem  2010;285:8743
  6. Activation of muscarinic acetylcholine receptors induces a nitric oxide-dependent long-term depression in rat medial prefrontal cortex.
    Authors: Huang and Hsu
    Cereb Cortex  2010;20:982
  7. Modulation of inhibitory activity by nitric oxide in the thalamus.
    Authors: Yang
    J Neurophysiol  2007;97:3386
  8. Peripheral analgesic blockade of hypernociception: activation of arginine/NO/cGMP/protein kinase G/ATP-sensitive K+ channel pathway.
    Authors: Sachs Et al.
    Proc Natl Acad Sci U S A  2004;101:3680
  9. High-Yield Method for Isolation and Culture of Endothelial Cells from Rat Coronary Blood Vessels Suitable for Analysis of Intracellular Calcium and Nitric Oxide Biosynthetic Pathways.
    Authors: Nistri Et al.
    Evid Based Complement Alternat Med  2002;4:32
  10. In vivo microdialysis study of a specific inhibitor of soluble guanylyl cyclase on the glutamate receptor/nitric oxide/cyclic GMP pathway.
    Authors: Fedele Et al.
    Br J Pharmacol  1996;119:590

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