Catalog Number: 1529
Chemical Name: 4-[(S)-[(2S,5R)-2,5-Dimethyl-4-(2-propenyl)-1-piperazinyl]phenylmethyl]-N,N-diethylbenzamide
Biological Activity
Potent and selective non-peptide δ-opioid receptor agonist (Ki = 0.63 nM). Displays > 8000-fold selectivity over μ-opioid receptors and is centrally active following systemic administration in vivo.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in 1eq. HCl
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective δ agonist (+)-4-[(αR)-α-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-<
    Calderon et al.
    J.Med.Chem., 1997;40:695
  2. Structure-activity relationships for SNC80 and related compounds at cloned human delta and mu opioid receptors.
    Knapp et al.
    J.Pharmacol.Exp.Ther., 1996;277:1284
  3. Behavioral effects of the delta-selective opioid agonist SNC80 and related compounds in rhesus monkeys.
    Negus et al.
    J.Pharmacol.Exp.Ther., 1998;286:362
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details


Contact Information

Molarity Calculator
Calculate the mass, volume or concentration required for a solution

The molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) x Volume (L) x Molecular Weight (g/mol)
An example of a molarity calculation using the molarity calculator:
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?

R&D Systems Guarantee

or select another batch:


Customer Information