Sodium 4-Phenylbutyrate

  ( 1 citations )    
Product Datasheet
Catalog Number:2682
Alternate Names:4-PB, Sodium phenylbutyrate
Chemical Name:4-Phenylbutyric acid, sodium salt
Product Details
Citations (1)
Reviews
Biological Activity
Histone deacetylase inhibitor that displays anticancer activity. Inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. Also inhibits protein isoprenylation, depletes plasma glutamine, increases production of fetal hemoglobin through transcriptional activation of the γ-globin gene and affects hPPARγ activation.
Technical Data
  • M.Wt:
    186.18
  • Formula:
    C10H11NaO2
  • Solubility:
    Soluble to 100 mM in water and to 25 mM in DMSO
  • Purity:
    >99
  • Storage:
    Desiccate at -20°C
  • CAS No:
    1716-12-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Sodium 4-Phenylbutyrate include:

1 Citations: Showing 1 - 1

  1. Cyclic mechanical stretch down-regulates cathelicidin antimicrobial peptide expression and activates a pro-inflammatory response in human bronchial epithelial cells.
    Authors: Karadottir Et al.
    Oncotarget  2015;3:e1483

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