Sodium 4-Phenylbutyrate

Catalog # Availability Size / Price Qty
Sodium 4-Phenylbutyrate | CAS No. 1716-12-7 | Class I Histone Deacetylases Inhibitors
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Description: Histone deacetylase inhibitor
Alternative Names: 4-PB, Sodium phenylbutyrate

Chemical Name: 4-Phenylbutyric acid, sodium salt

Purity: ≥99%

Product Details
Citations (2)

Biological Activity

Sodium 4-Phenylbutyrate is a histone deacetylase inhibitor that displays anticancer activity. Inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. Sodium 4-Phenylbutyrate also inhibits protein isoprenylation, depletes plasma glutamine, increases production of fetal hemoglobin through transcriptional activation of the γ-globin gene and affects hPPARγ activation.

Technical Data

Soluble to 100 mM in water and to 25 mM in DMSO
Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Sodium 4-Phenylbutyrate

The citations listed below are publications that use Tocris products. Selected citations for Sodium 4-Phenylbutyrate include:

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