Catalog Number: 2821
Chemical Name: Trisodium vanadate
Biological Activity
Inhibitor of protein tyrosine phosphatases, alkaline phosphatases and ATPases. Suppresses p53-mediated apoptosis by transcription-dependent and -independent pathways.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Inhibition of small-intestinal sugar absorption mediated by sodium orthovanadate Na3VO4 in rats and its mechanisms.
    Ai et al.
    World J.Gastroenterol., 2004;10:3612
  2. Therapeutic time window and dose dependence of neuroprotective effects of sodium orthovanadate following transient middle cerebral artery occlusion in rats.
    Hasegawa et al.
    J.Pharmacol.Exp.Ther., 2006;317:875
  3. Sodium orthovanadate enhances proliferation of progenitor cells in the adult rat subventricular zone after focal cerebral ischemia.
    Matsumoto et al.
    J.Pharmacol.Exp.Ther., 2006;318:982
  4. Sodium orthovanadate inhibits p53-mediated apoptosis.
    Morita et al.
    Cancer Res., 2010;70:257
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