Spautin 1

   
Product Datasheet
Catalog Number:5197
Chemical Name:6-Fluoro-N-[(4-Fluorophenyl)methyl]-4-quinazolinamine
Product Details
Reviews
Biological Activity
Inhibitor of autophagy; inhibits USP10 and USP13 activity (IC50 values are 0.6 and 0.7 μM respectively) and promotes degradation of Vps34 (class III PI 3-kinase) complexes. Selectively promotes apoptosis of cancer cells under starvation conditions. Prevents the PDGF-induced conversion from the contractile to synthetic phenotype in vascular smooth muscle cells.
Technical Data
  • M.Wt:
    271.26
  • Formula:
    C15H11F2N3
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    1262888-28-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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