Polyamine which produces a variety of modulatory effects on the NMDA receptor channel, acting through a specific site on the complex which can cause both agonist and antagonist effects.
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Multiple effects of spermine on N-methyl-D-aspartic acid receptor responses of rat cultured hippocampal neurones.
Benveniste and Mayer
Investigation of the actions and antagonist activity of some polyamine analogues in vivo.
Doyle and Shaw
Polyamines modulate the neurotoxic effects of NMDA in vivo.
Munir et al.
Brain Res., 1993;616:163
Modulation of channel function by polyamines.
The citations listed below are publications that use Tocris products. Selected citations for Spermine tetrahydrochloride include:
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