Catalog Number: 0958
Chemical Name: N,N'-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride
Biological Activity
Polyamine which produces a variety of modulatory effects on the NMDA receptor channel, acting through a specific site on the complex which can cause both agonist and antagonist effects.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Multiple effects of spermine on N-methyl-D-aspartic acid receptor responses of rat cultured hippocampal neurones.
    Benveniste and Mayer
    J.Physiol., 1993;464:131
  2. Investigation of the actions and antagonist activity of some polyamine analogues in vivo.
    Doyle and Shaw
    Br.J.Pharmacol., 1998;124:386
  3. Polyamines modulate the neurotoxic effects of NMDA in vivo.
    Munir et al.
    Brain Res., 1993;616:163
  4. Modulation of channel function by polyamines.
    TiPS, 1996;17:22
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details


Contact Information

Molarity Calculator
Calculate the mass, volume or concentration required for a solution

The molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) x Volume (L) x Molecular Weight (g/mol)
An example of a molarity calculation using the molarity calculator:
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?

R&D Systems Guarantee

or select another batch:


Customer Information