Spermine tetrahydrochloride

  ( 7 citations )    
Product Datasheet
Catalog Number:0958
Chemical Name:N,N'-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride
Product Details
Citations (7)
Reviews
Biological Activity
Polyamine which produces a variety of modulatory effects on the NMDA receptor channel, acting through a specific site on the complex which can cause both agonist and antagonist effects.
Technical Data
  • M.Wt:
    348.19
  • Formula:
    C10H26N4.4HCl
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Desiccate at +4°C
  • CAS No:
    306-67-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Spermine tetrahydrochloride include:

7 Citations: Showing 1 - 7
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  1. Acid-sensing ion channel 1a drives AMPA receptor plasticity following ischaemia and acidosis in hippocampal CA1 neurons.
    Authors: Quintana Et al.
    Proc Natl Acad Sci U S A  2015;593:4373
  2. Auxiliary Subunit GSG1L Acts to Suppress Calcium-Permeable AMPA Receptor Function.
    Authors: McGee Et al.
    J Neurosci  2015;35:16171
  3. Molecular mechanisms contributing to TARP regulation of channel conductance and polyamine block of calcium-permeable AMPA receptors.
    Authors: Soto Et al.
    J Neurosci  2014;34:11673
  4. NMDA receptor signaling in oligodendrocyte progenitors is not required for oligodendrogenesis and myelination.
    Authors: Biase Et al.
    J Physiol  2011;31:12650
  5. Bidirectional plasticity of calcium-permeable AMPA receptors in oligodendrocyte lineage cells.
    Authors: Zonouzi Et al.
    Nat Neurosci  2011;14:1430
  6. Selective regulation of long-form calcium-permeable AMPA receptors by an atypical TARP, gamma-5.
    Authors: Soto Et al.
    Nat Neurosci  2009;12:277
  7. Stress-induced changes in nucleus accumbens glutamate synaptic plasticity.
    Authors: Campioni Et al.
    J Neurosci  2009;101:3192

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