Catalog Number: 1435
Chemical Name: 9-(Tetrahydro-2-furanyl)-9H-purin-6-amine
Biological Activity
Inhibitor of adenylyl cyclase (IC50 = 1.4 μM). Inhibits PGE1-stimulated increases in cAMP levels in intact human platelets.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 50 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Role of cyclic nucleotides in vasodilations of the rat thoracic aorta induced by adenosine analogues.
    Hourani et al.
    Br.J.Pharmacol., 2001;133:833
  2. Inhibition of adenylate cyclase of catfish and rat hepatocyte membranes by 9-(tetrahydro-2-furyl)adenine (SQ 22536).
    Fabbri et al.
    J.Enzyme Inhib., 1991;5:87
  3. Inhibition of adenylate cyclase in human blood platelets by 9-substituted adenine derivatives.
    Harris et al.
    J.Cyclic Nucleotide Res., 1979;5:125
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