Squarunkin A hydrochloride

Key Product Details

Product Description

Squarunkin A hydrochloride is a potent inhibitor of UNC119 chaperone protein-cargo interaction (IC₅₀ = 10 nM for inhibition of UNC119A - myristoylated Src N-terminal peptide interaction). Disrupts activation of Src kinase in vitro.

Product Specifications for Squarunkin A hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Squarunkin A hydrochloride

The following data is based on the product molecular weight 560.01.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	3.57 mL	17.86 mL	35.71 mL
2.5 mM	0.71 mL	3.57 mL	7.14 mL
5 mM	0.36 mL	1.79 mL	3.57 mL
25 mM	0.07 mL	0.36 mL	0.71 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Mejuch Small-molecule inhibition of the UNC119-cargo interaction. Angew.Chem.Int.Ed. 2017 PMID: 28471079

Product Documents for Squarunkin A hydrochloride