SR 57227 hydrochloride

Tocris Bioscience | Catalog # 1205

Potent and selective 5-HT3 agonist
Tocris Bioscience

Key Product Details

Description

Potent and selective 5-HT3 agonist
View all 5-HT3 Receptor Agonists »

Product Description

SR 57227 hydrochloride is a high affinity, selective 5-HT3 receptor agonist, active in vivo and CNS penetrant.

Product Specifications for SR 57227 hydrochloride

Molecular Weight

248.15

Formula

C10H14ClN3.HCl

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

1-(6-Chloro-2-pyridinyl)-4-piperidinamine hydrochloride

CAS Number

77145-61-0

PubChem ID

131746

InChI Key

FUMINTAAUJUVMP-UHFFFAOYSA-N

SMILES

Cl.NC1CCN(CC1)C1=NC(Cl)=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 24.82 100
DMSO 24.82 100

Preparing Stock Solutions for SR 57227 hydrochloride

The following data is based on the product molecular weight 248.15.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.03 mL 20.15 mL 40.30 mL
5 mM 0.81 mL 4.03 mL 8.06 mL
10 mM 0.40 mL 2.01 mL 4.03 mL
50 mM 0.08 mL 0.40 mL 0.81 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 15 publications citing the usage of this product.

Product Documents for SR 57227 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SR 57227 hydrochloride

For research use only

Citations for SR 57227 hydrochloride

Customer Reviews for SR 57227 hydrochloride (1)

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  • PGE2 release
    Name: jialie luo
    Species: Mouse
    Assay Type: In Vitro
    Verified Customer | Posted 01/10/2018
    SR 57227 hydrochloride was used to stimulate macrophages as negative control.
    SR 57227 hydrochloride 1205

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