SR 57227 hydrochloride
Chemical Name: 1-(6-Chloro-2-pyridinyl)-4-piperidinamine hydrochloride
Biological ActivityA high affinity, selective 5-HT3 receptor agonist, active in vivo and CNS penetrant.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
SR 57227A: a potent and selective agonist at central and peripheral 5-HT3 receptors in vitro and in vivo.
Bachy et al.
5-HT3-like receptors in the rat medial prefrontal cortex: further pharmacological characterization.
Edwards et al.
Brain Res., 1996;733:21
Citation for SR 57227 hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for SR 57227 hydrochloride include:
1 Citation: Showing 1 - 1
Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms.
Authors: Otvos Et al.
Dent Res J (Isfahan) 2015;7:2336
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SR 57227 hydrochloride was used to stimulate macrophages as negative control.