Catalog Number: 1205
Chemical Name: 1-(6-Chloro-2-pyridinyl)-4-piperidinamine hydrochloride
Biological Activity
A high affinity, selective 5-HT3 receptor agonist, active in vivo and CNS penetrant.
Technical Data
  • M.Wt:
    248.15
  • Formula:
    C10H14ClN3.HCl
  • Solubility:
    Soluble to 50 mM in water and to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    77145-61-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. SR 57227A: a potent and selective agonist at central and peripheral 5-HT3 receptors in vitro and in vivo.
    Bachy et al.
    Eur.J.Pharmacol., 1993;237:299
  2. 5-HT3-like receptors in the rat medial prefrontal cortex: further pharmacological characterization.
    Edwards et al.
    Brain Res., 1996;733:21
Citations:

The citations listed below are publications that use Tocris products. Selected citations for SR 57227 hydrochloride include:

1 Citations: Showing 1 - 1

  1. Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms.
    Authors: Otvos Et al.
    Dent Res J (Isfahan) 2015;7:2336

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