Potent and selective β3
adrenoceptor antagonist (IC50
values are 40, 408 and 648 nM for β3
receptors respectively). Orally active in vivo
. Also available as part of the β-Adrenoceptor Antagonist Tocriset™
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Synthesis of S-[3-(4(5)-imidazolyl)propyl]-N-[2-(4-[125I]-iodophenylethyl]isothiourea sulfate [125I]-iodophenpropit), a new probe for histamine H3 receptor binding sites.
Menge et al.
J.Labelled Comp.Radiopharm. XXXI, 1992;10:781
Functional identification of rat atypical β-adrenoceptors by the first β3-selective antagonists, aryloxypropanolaminotetralins.
Manara et al.
Stimulation of β3-adrenoceptors causes phosphorylation of p38 mitogen-activated protein kinase via a stimulatory G protein-dependent pathway in 3T3-L1 adipocytes.
Mizuno et al.
The citations listed below are publications that use Tocris products. Selected citations for SR 59230A hydrochloride include:
Showing Results 1 - 10 of 10