Chemical Name: Ethyl 3-[[[(4-chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-1-pyrrolidinecarboxylate
Biological ActivitySR 9009 is a Rev-Erbα/β agonist (EC50 = 710 nM; Kd = 800 nM). Alters circadian locomotor activity and core clock hypothalamic gene expression in mice. Induces weight loss in diet-induced obese mice. Brain penetrant.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Small molecule tertiary amines as agonists of the nuclear hormone receptor Rev-erbα.
Shin et al.
Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists.
Solt et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for SR 9009
There are currently no reviews for this product. Be the first to review SR 9009 and earn rewards!
Have you used SR 9009?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image