Recombinant Human SRGN His Protein

Novus Biologicals | Catalog # NBP1-72483

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
View all Serglycin/SRGN Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 28-158 of Human SRGN

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMYPTRR ARYQWVRCNP DSNSANCLEE KGPMFELLPG ESNKIPRLRT DLFPKTRIQD LNRIFPLSED YSGSGFGSGS GSGSGSGSGF LTEMEQDYQL VDESDAFHDN LRSLDRNLPS DSQDLGQHGL EEDFML

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

17.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human SRGN His Protein

SDS-PAGE: Recombinant Human SRGN His Protein [NBP1-72483]

SDS-PAGE: Recombinant Human SRGN His Protein [NBP1-72483]

SDS-Page: Recombinant Human SRGN Protein [NBP1-72483] - 15% SDS-PAGE (3 ug).

Formulation, Preparation, and Storage

NBP1-72483
Formulation 20 mM Tris-HCl buffer (pH 8.0), 10% glycerol, 2 mM DTT, 0.15 M NaCl
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Serglycin/SRGN

SRGN is a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. Recombinant human SRGN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

Hematopoietic Proteoglycan Core Protein

Alternate Names

SRGN

Gene Symbol

SRGN

Additional Serglycin/SRGN Products

Product Documents for Recombinant Human SRGN His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human SRGN His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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