SSM 3 trifluoroacetate
Chemical Name: rel-N,N''-[[(1R,3S,4S,6R)-4,6-Bis[(aminoiminomethyl)amino]-1,3-cyclohexanedyil]bis(oxy-4,1-phenylene)]bisguanidine tetratrifluoroacetate salt
Biological ActivitySSM 3 trifluoroacetate is a potent furin inhibitor (EC50 = 54 nM). Blocks furin-dependent cell surface processing of anthrax protective antigen-83 in vitro.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Selective and potent furin inhibitors protect cells from anthrax without significant toxicity.
Int.J.Biochem.Cell Biol., 2010;42:987
Citations for SSM 3 trifluoroacetate
The citations listed below are publications that use Tocris products. Selected citations for SSM 3 trifluoroacetate include:
2 Citations: Showing 1 - 2
An Arginine-Rich Motif in the ORF2 capsid protein regulates the hepatitis E virus lifecycle and interactions with the host cell.
Authors: Hervouet Et al.
PLoS Pathog. 2022;18:e1010798
Furin inhibitors block SARS-CoV-2 spike protein cleavage to suppress virus production and cytopathic effects.
Authors: Cheng Et al.
Cell Rep. 2020;33
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