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StRIP16

Catalog #: 6575 Datasheet / COA / SDS

Discontinued Product

6575 has been discontinued.
View all Other Small Monomeric GTPase Inhibitors products.
StRIP16
1 Image
Description: Rab8a GTPase-binding stapled peptide
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Biological Activity

StRIP16 is a rab8a GTPase-binding stapled peptide (Kd = 12.7 μM). Cell permeable; localizes to the endomembrane system.

Technical Data

M.Wt:
2300.61
Formula:
C116H154N24O26
Sequence:
DNEXQWFXYHLXFFNXV

(Modifications: Asp-1 = N-terminal Ac, X = (S)-2-(4-pentenyl)alanine, X-4 and X-8 stapled together with a double bond, X-12 and X-16 stapled together with a double bond, Val-17 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in 40% acetonitrile / water
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Protease-resistant and cell-permeable double-stapled peptides targeting the Rab8a GTPase.
    Cromm et al.
    ACS Chem.Biol., 2016;11:2375

Product Datasheets

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Reconstitution Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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