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Description: Rab8a GTPase-binding stapled peptide
Product Details

Biological Activity

Rab8a GTPase-binding stapled peptide (Kd = 12.7 μM). Cell permeable; localizes to the endomembrane system.

Technical Data


(Modifications: Asp-1 = N-terminal Ac, X = (S)-2-(4-pentenyl)alanine, X-4 and X-8 stapled together with a double bond, X-12 and X-16 stapled together with a double bond, Val-17 = C-terminal amide)

Soluble to 1 mg/ml in 40% acetonitrile / water
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Protease-resistant and cell-permeable double-stapled peptides targeting the Rab8a GTPase.
    Cromm et al.
    ACS Chem.Biol., 2016;11:2375

Product Datasheets

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