Biological ActivityRab8a GTPase-binding stapled peptide (Kd = 12.7 μM). Cell permeable; localizes to the endomembrane system.
(Modifications: Asp-1 = N-terminal Ac, X = (S)-2-(4-pentenyl)alanine, X-4 and X-8 stapled together with a double bond, X-12 and X-16 stapled together with a double bond, Val-17 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Protease-resistant and cell-permeable double-stapled peptides targeting the Rab8a GTPase.
Cromm et al.
ACS Chem.Biol., 2016;11:2375
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