Sumatriptan succinate

Catalog # Availability Size / Price Qty
3586/10
3586/50
Cat.No. 3586 - Sumatriptan succinate | C14H21N3O2S.C4H6O4 | CAS No. 103628-48-4
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Description: 5-HT1A/1B/1D receptor agonist
Alternative Names: GR 43175

Chemical Name: 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate

Purity: ≥99%

Product Details
Citations (1)
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Biological Activity

5-HT1 receptor agonist (Ki values are 17, 27 and 100 nM at 5-HT1D, 5-HT1B and 5-HT1A receptors respectively). Antimigraine agent.

Technical Data

M.Wt:
413.49
Formula:
C14H21N3O2S.C4H6O4
Solubility:
Soluble to 100 mM in water and to 75 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
103628-48-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Effect of sumatriptan in different models of pain in rats.
    Ottani et al.
    Eur.J.Pharmacol., 2004;497:181
  2. Sumatriptan (GR 43175) interacts selectivity with 5-HT1B and 5-HT1D binding sites.
    Peroutka and McCarthy
    Eur.J.Pharmacol., 1989;163:133
  3. Sumatriptan in acute migraine: pharmacology and review of world experience.
    Peroutka
    Headache, 1990;30:554

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Citation for Sumatriptan succinate

The citations listed below are publications that use Tocris products. Selected citations for Sumatriptan succinate include:

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