Sumatriptan succinate

Tocris Bioscience | Catalog # 3586

5-HT1A, 5-HT1B and 5-HT1D agonist
Tocris Bioscience

Key Product Details

Description

5-HT1A, 5-HT1B and 5-HT1D agonist

Alternative Names

GR 43175
View all Non-selective 5-HT1 Receptor Agonists »

Product Description

Sumatriptan succinate is a 5-HT1 receptor agonist (Ki values are 17, 27 and 100 nM at 5-HT1D, 5-HT1B and 5-HT1A receptors respectively). Antimigraine agent.

Product Specifications for Sumatriptan succinate

Molecular Weight

413.49

Formula

C14H21N3O2S.C4H6O4

Storage

Store at +4°C

Purity

≥99% (HPLC)

Chemical Name

3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate

CAS Number

103628-48-4

PubChem ID

59772

InChI Key

PORMUFZNYQJOEI-UHFFFAOYSA-N

SMILES

O=S(CC1=CC=C(NC=C2CCN(C)C)C2=C1)(NC)=O.O=C(CCC(O)=O)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 41.35 100
DMSO 31.01 75

Preparing Stock Solutions for Sumatriptan succinate

The following data is based on the product molecular weight 413.49.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.42 mL 12.09 mL 24.18 mL
5 mM 0.48 mL 2.42 mL 4.84 mL
10 mM 0.24 mL 1.21 mL 2.42 mL
50 mM 0.05 mL 0.24 mL 0.48 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

x
=
x

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.

Product Documents for Sumatriptan succinate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Sumatriptan succinate

For research use only

Citations for Sumatriptan succinate

Customer Reviews for Sumatriptan succinate (1)

4 out of 5
1 Customer Rating
5 Stars
0%
4 Stars
100%
3 Stars
0%
2 Stars
0%
1 Stars
0%

Have you used Sumatriptan succinate?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Customer Images

Showing  1 - 1 of 1 review Showing All
Filter By:
Clear Filters X
  • Inhibition of Synaptic Transmission in the VP
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vivo
    Verified Customer | Posted 02/02/2020
    sumatriptan (1 μΜ)
    Sumatriptan succinate 3586

There are no reviews that match your criteria.

Showing  1 - 1 of 1 review Showing All