Chemical Name: 5-[1-[(2-Aminophenyl)imino]ethyl]-1,6-dihydroxy-4-methyl-2(1H)-pyridone
Biological ActivityNon-peptide calcitonin (CT) receptor agonist that fully stimulates cAMP production in CHO/hCTR cells (EC50 = 21 μM). Causes a significant reduction in serum calcium concentrations in vivo following i.p. administration.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Discovery of a non-peptide small molecule that selectively mimics the biological actions of calcitonin.
Katayama et al.
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VersaClone cDNA Plasmids
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