SYM 2081

Catalog # Availability Size / Price Qty
0903/10
0903/50
Cat.No. 0903 - SYM 2081 | C6H11NO4 | CAS No. 31137-74-3
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Description: Highly selective kainate agonist

Chemical Name: (2S,4R)-4-Methylglutamic acid

Purity: ≥97%

Product Details
Citations (5)
Reviews

Biological Activity

Potent and highly selective kainate receptor agonist, with an IC50 for inhibition of [3H]-kainate binding of 35 nM and almost 3,000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively. Also selectively inhibits the cloned excitatory amino acid transporter EAAT2 at higher concentrations. Also available as part of the Excitatory Amino Acid Transporter Inhibitor Tocriset™ and Kainate Receptor Tocriset™.

Technical Data

M.Wt:
161.16
Formula:
C6H11NO4
Solubility:
Soluble to 50 mM in water
Purity:
≥97%
Storage:
Store at RT
CAS No:
31137-74-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Additional Information

Licensing Caveats:
Sold with the permission of Annovis Inc.

Product Datasheets

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Citations for SYM 2081

The citations listed below are publications that use Tocris products. Selected citations for SYM 2081 include:

5 Citations: Showing 1 - 5

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