Tandospirone hydrochloride

Catalog # Availability Size / Price Qty
2854/10
2854/50
Tandospirone hydrochloride | CAS No. 99095-10-0 | 5-HT1 Receptor Agonists
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Description: Selective 5-HT1A partial agonist
Alternative Names: SM-3997

Chemical Name: (3aR,4S,7R,7aS)-rel-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione hydrochloride

Purity: ≥98%

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Biological Activity

5-HT1A receptor partial agonist (Ki = 27 nM) that displays selectivity over 5-HT2, 5-HT1C, α1, α2, D1 and D2 receptors (Ki values ranging from 1300 - 41000 nM). Inactive at 5-HT uptake sites, 5-HT1B, β-adrenergic, muscarinic and benzodiazepine receptors. Displays anxiolytic activity.

Technical Data

M.Wt:
419.95
Formula:
C21H29N5O2.HCl
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in water
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
99095-10-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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