Catalog Number: 4811
Biological Activity
Nrf2 activator; inhibits Nrf2/Keap1 interaction. Induces upregulation of Nrf2 pathway downstream gene expression including heme-oxygenase 1. Suppresses LPS-induced TNF-α expression in THP-1 cells.
Technical Data
  • M.Wt:
    3173.6
  • Formula:
    C137H230N48O39
  • Sequence:
    YGRKKRRQRRRLQLDEETGEFLPIQ
  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    1362661-34-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Anti-inflammatory effect of a cell-penetrating peptide targeting the Nrf2/Keap1 interaction.
    Steel et al.
    ACS Med.Chem.Lett., 2012;3:407

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