TAT-GluA2 3Y
Description: Inhibitor of AMPA receptor endocytosis
Biological Activity
TAT-GluA2 3Y is an inhibitor of AMPA receptor endocytosis. Induces increased hind paw withdrawal latencies following thermal and mechanical stimuli in rats. Also exhibits antinociceptive effects in a rat model of neuropathic pain. Rescues pentobarbital-induced memory retrieval deficits in a rat model of learning and memory.Technical Data
M.Wt:
2634
Formula:
C115H185N43O29
Sequence:
YGRKKRRQRRRYKEGYNVYG
Solubility:
Soluble to 1 mg/ml in water
Storage:
Store at -20°C
CAS No:
1404188-93-7
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Inhibition of AMPAR endocytosis alleviates pentobarbital-induced spatial memory deficits and synaptic depression.
Wang et al.
Behav.Brain Res., 2018;339:66
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