Taxol Janelia Fluor® 526

Tocris Bioscience | Catalog # 7315

Green-fluorescent taxol derivative; binds microtubules. Used for: microtubules imaging. Application: confocal microscopy, super resolution microscopy. Suitable for live cell imaging
Tocris Bioscience

Key Product Details

Description

Green-fluorescent taxol derivative; binds microtubules. Used for: microtubules imaging. Application: confocal microscopy, super resolution microscopy. Suitable for live cell imaging

Alternative Names

Janelia Fluor 526-TXL

Wavelength

Excitation = 531 nm, Emission = 549 nm
View all Microtubule Probes »

Product Description

Key information: Taxol Janelia Fluor® 526 is a fluorogenic, green-fluorescent taxol derivative for direct imaging of the microtubule cytoskeleton. Suitable for live cell imaging.

Used for: direct imaging of the microtubule cytoskeleton.

Application: confocal microscopy, Super Resolution Microscopy (SRM) including STED.

Properties and Photophysical Data: Taxol Janelia Fluor® 526 is fluorogenic: it fluoresces only once bound to microtubules, enabling hassle-free no-wash experiments. Excitation and emission maxima (λ) are 531 nm and 549 nm, respectively; quantum yield = 0.87; extinction coefficient = 118,000 M-1cm-1.

Licensing Information

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus

Optical Data

Taxol Janelia Fluor<sup>®</sup> 526 Dye Spectra
Emission Color Yellow
λabs 531 nm
λem 549 nm
Extinction Coefficient (ε) 118000 M-1cm-1
Quantum Yield (φ) 0.87
Application Confocal Microscopy, Super Resolution Microscopy (SRM), STED

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer
Spectra Viewer

Product Specifications for Taxol Janelia Fluor® 526

Molecular Weight

1507.42

Formula

C73H74F6N4O17.CF3CO2H

Storage

Store at -20°C

Purity

≥85% (HPLC)

Chemical Name

4-((8-(((1S,2R)-3-(((2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-12-(benzoyloxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-9-yl)oxy)-2-hydroxy-3-oxo-1-phenylpropyl)amino)-8-oxooctyl)carbamoyl)-2-(3-(3,3-difluoroazetidin-1-ium-1-ylidene)-6-(3,3-difluoroazetidin-1-yl)-2,7-difluoro-3H-xanthen-9-yl)benzoate trifluoroacetate

CAS Number

2410613-93-1

InChI Key

WYTXGBVNWCQFKK-SOCHEKDQSA-N

SMILES

[H][C@@]12C[C@@H]([C@]3(C([C@@H](C4=C([C@@H](OC([C@@H]([C@H](C5=CC=CC=C5)NC(CCCCCCCNC(C6=CC(C7=C8C=C(/C(C=C8OC9=C7C=C(C(N%10CC(F)(C%10)F)=C9)F)=[N+]%11CC(F)(C/%11)F)F)=C(C([O-])=O)C=C6)=O)=O)O)=O)C[C@@]([C@H]([C@@]3([C@]1(OC(C)=O)CO2)[H])OC(C%12=CC=CC=C%12)=O)(C4(C)C)O)C)O)=O)C)O.O=C(O[H])C(F)(F)F

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 15.07 10

Preparing Stock Solutions for Taxol Janelia Fluor® 526

The following data is based on the product molecular weight 1507.42.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 6.63 mL 33.17 mL 66.34 mL
0.5 mM 1.33 mL 6.63 mL 13.27 mL
1 mM 0.66 mL 3.32 mL 6.63 mL
5 mM 0.13 mL 0.66 mL 1.33 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

x
=
x

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product.

Product Documents for Taxol Janelia Fluor® 526

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Taxol Janelia Fluor® 526

For research use only

Customer Reviews for Taxol Janelia Fluor® 526

There are currently no reviews for this product. Be the first to review Taxol Janelia Fluor® 526 and earn rewards!

Have you used Taxol Janelia Fluor® 526?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card