Taxol Janelia Fluor® 646

Tocris Bioscience | Catalog # 6266

Red-fluorescent taxol derivative. Used for: microtubule staining. Application: confocal microscopy, fluorescence microscopy; protocol available
Tocris Bioscience

Key Product Details

Description

Red-fluorescent taxol derivative. Used for: microtubule staining. Application: confocal microscopy, fluorescence microscopy; protocol available

Wavelength

Excitation = 655 nm, Emission = 671 nm
View all Microtubule Probes »

Product Description

Key information

: Taxol Janelia Fluor® 646 is a red-fluorescent taxol derivative for direct imaging of the microtubule cytoskeleton.

Used for: microtubule cytoskeleton imaging.

Application: confocal microscopy, fluorescence microscopy.

Properties and Photophysical Data: Excitation and emission maxima (λ) are 655 nm and 671 nm, respectively.

For more information on how Taxol-Janelia Fluor® 646 may be used, see our protocol.

Scientific Data Images for Taxol Janelia Fluor® 646

COS7 cells dye-labeled with Taxol Janelia Fluor 646

Application of Taxol Janelia Fluor® 646, dye on COS7 cells.

COS7 cells were labeled with 3 µM Taxol Janelia Fluor® 646 for one hour at 37°C. Images were taken on a Leica TCS SP8 Confocal Laser Scanning Microscope. All images kindly provided by Prof. Christian Soeller, University of Exeter; acquired by Evelina Lucinskaite, Anna Meletiou and Alexander Clowsley.

Licensing Information

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus

Optical Data

Taxol Janelia Fluor<sup>®</sup> 646 Dye Spectra
Emission Color Red
λabs 655 nm
λem 671 nm
Application Fluorescence Microscopy, Confocal Microscopy

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer
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Product Specifications for Taxol Janelia Fluor® 646

Molecular Weight

1403.62

Formula

C79H82N4O18Si

Storage

Store at -20°C

Purity

≥90% (HPLC)

Chemical Name

2-(3-(Azetidin-1-ium-1-ylidene)-7-(azetidin-1-yl)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)-4-(((2S)-1-(((2aR,4S,4aS,6R,9S,11S,12S,12bS)-6,12b-diacetoxy-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-4-yl)oxy)-1-oxopropan-2-yl)carbamoyl)benzoate

SMILES

O=C(C)O[C@]12C([C@@]3(C)[C@@H](OC([C@H](C)NC(C4=CC=C(C([O-])=O)C(C5=C(C=C/6)C([Si](C)(C)C7=C5C=CC(N8CCC8)=C7)=CC6=[N+]9CCC\9)=C4)=O)=O)C[C@H]1OC2)[C@H](OC(C%10=CC=CC=C%10)=O)[C@@]%11(O)C(C)(C)C([C@@H](OC(C)=O)C3=O)=C(C)[C@@H](OC([C@H](O)[C@H](C%12=CC=CC=C%12)NC(C%13=CC=CC=C%13)=O)=O)C%11

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 28.07 20

Preparing Stock Solutions for Taxol Janelia Fluor® 646

The following data is based on the product molecular weight 1403.62.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 3.56 mL 17.81 mL 35.62 mL
1 mM 0.71 mL 3.56 mL 7.12 mL
2 mM 0.36 mL 1.78 mL 3.56 mL
10 mM 0.07 mL 0.36 mL 0.71 mL

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

There are currently no references for this product.

Product Documents for Taxol Janelia Fluor® 646

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Taxol Janelia Fluor® 646

For research use only

Citations for Taxol Janelia Fluor® 646

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