Taxol Janelia Fluor® 646

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Taxol Janelia Fluor® 646 | Microtubule Probes
1 Image
Description: Red fluorescent taxol derivative; probe for microtubule staining; protocol available

Chemical Name: 2-(3-(Azetidin-1-ium-1-ylidene)-7-(azetidin-1-yl)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)-4-(((2S)-1-(((2aR,4S,4aS,6R,9S,11S,12S,12bS)-6,12b-diacetoxy-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-4-yl)oxy)-1-oxopropan-2-yl)carbamoyl)benzoate

Purity: ≥98%

Product Details

Biological Activity

Red fluorescent taxol derivative for direct imaging of the microtubule cytoskeleton. Fluorogenic: fluoresces only once bound to microtubules, enabling hassle-free no-wash experiments. Protocol available. Excitation maximum = 655 nm; emission maximum = 671 nm.

Application of Taxol Janelia Fluor® 646 dye on COS7 cells

Taxol Janelia Fluor® 646 Dye-labeled COS7 cells

Application of Taxol Janelia Fluor® 646, dye on COS7 cells; COS7 cells were labeled with 3 µM Taxol Janelia Fluor® 646 for one hour at 37°C. Images were taken on a Leica TCS SP8 Confocal Laser Scanning Microscope.

All images kindly provided by Prof. Christian Soeller, University of Exeter; acquired by Evelina Lucinskaite, Anna Meletiou and Alexander Clowsley.

Optical Data for Taxol Janelia Fluor® 646

Taxol Janelia Fluor<sup>®</sup> 646 Dye Spectra
λabs 655 nm
λem 671 nm

Technical Data

Soluble to 20 mM in DMSO
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus

Product Datasheets

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