Taxol Janelia Fluor® 646

Catalog # Availability Size / Price Qty
6266/1
Fluorescent Probes Small Molecule
1 Image
Description: Red fluorescent taxol derivative

Chemical Name: 2-(3-(Azetidin-1-ium-1-ylidene)-7-(azetidin-1-yl)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)-4-(((2S)-1-(((2aR,4S,4aS,6R,9S,11S,12S,12bS)-6,12b-diacetoxy-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-4-yl)oxy)-1-oxopropan-2-yl)carbamoyl)benzoate

Purity: ≥98%

Product Details
Reviews

Biological Activity

Red fluorescent taxol derivative for direct imaging of the microtubule cytoskeleton. Fluorogenic: fluoresces only once bound to microtubules, enabling hassle-free no-wash experiments. Protocol available. Excitation maximum = 646 nm; emission maximum = 664 nm.

Application of Taxol Janelia Fluor® 646 dye on COS7 cells

Taxol Janelia Fluor® 646 Dye-labeled COS7 cells

Application of Taxol Janelia Fluor® 646, dye on COS7 cells; COS7 cells were labeled with 3 µM Taxol Janelia Fluor® 646 for one hour at 37�C. Images were taken on a Leica TCS SP8 Confocal Laser Scanning Microscope.

All images kindly provided by Prof. Christian Soeller, University of Exeter; acquired by Evelina Lucinskaite, Anna Meletiou and Alexander Clowsley.

Optical Data for Taxol Janelia Fluor® 646

λabs 655 nm
λem 671 nm

Technical Data

M.Wt:
1403.62
Formula:
C79H82N4O18Si
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus

Product Datasheets

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Reconstitution Calculator

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