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TC-A 2317 hydrochloride

   
Product Datasheet
Catalog Number:4066
Chemical Name:2-[(5-Hydroxy-1,5-dimethylhexyl)amino]-4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-3-pyridinecarbonitrile hydrochloride
Product Details
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Biological Activity
Potent Aurora kinase A inhibitor (Ki = 1.2 nM compared to 101 nM for inhibition of Aurora kinase B). Selective over 60 other kinases (IC50 values > 1000 nM). Exhibits good cell permeability and antitumor activity.
Technical Data
  • M.Wt:
    392.93
  • Formula:
    C19H28N6O.HCl
  • Solubility:
    Soluble to 100 mM in DMSO and to 50 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    1245907-03-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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