TC JL 37

Catalog # Availability Size / Price Qty
6125/50
6125/10
TC JL 37 | CAS No. 1258294-34-6 | JAK Kinase Inhibitors
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Description: Potent TYK2 inhibitor

Chemical Name: 2-Chloro-4-cyano-6-fluoro-N-[2-[[[(1R,2R)-2-fluorocyclopropyl]carbonyl]amino]-4-pyridinyl]benzamide

Purity: ≥98%

Product Details
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Biological Activity

TC JL 37 is a potent inhibitor of tyrosine kinase 2 (TYK2, Ki = 1.6 nM). Shows some selectivity for TYK2 over JAK1/2/3. Inhibits IFNγ production in vivo in mice. Orally bioavailable.

Technical Data

M.Wt:
376.74
Formula:
C17H11ClF2N4O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1258294-34-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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