TC Mps1 12

Catalog # Availability Size / Price Qty
4750/10
4750/50
TC Mps1 12 | CAS No. 1206170-62-8 | TTK/Mps1 Kinase Inhibitors
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Description: Potent and selective Mps1 kinase inhibitor

Chemical Name: 4-[[4-Amino-5-cyano-6-[(1,1-dimethylethyl)amino]-2-pyridinyl]amino]benzamide

Purity: ≥99%

Product Details
Citations (1)
Reviews

Biological Activity

Potent and selective monopolar spindle 1 (Mps1) inhibitor (IC50 = 6.4 nM). Selective for Mps1 over a panel of 95 kinases including JNK. Inhibits A549 lung carcinoma cell proliferation and attenuates A549 cell xenograft growth in mice. Orally active.

Technical Data

M.Wt:
324.38
Formula:
C17H20N6O
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol with gentle warming
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
1206170-62-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for TC Mps1 12

The citations listed below are publications that use Tocris products. Selected citations for TC Mps1 12 include:

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