Potent non-peptide oxytocin receptor partial agonist (EC50
values are 33 nM and 850 nM for the oxytocin receptor and V2
vasopressin receptor respectively). Also a V1a
vasopressin receptor antagonist (Ki
= 330 nM). Active in vivo
in a rat model of uterine response.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Subtlety of the structure-affinity and structure-efficacy relationships around a nonpeptide oxytocin receptor agonist.
Frantz et al.
Non-peptide oxytocin agonists.
Pitt et al.