Amino Acid Sequence: MAECPTLGEA VTDHPDRLWA WEKFVYLDEK QHAWLPLTIE IKDRLQLRVL LRREDVVLGR PMTPTQIGPS LLPIMWQLYP DGRYRSSDSS FWRLVYHIKI DGVEDMLLEL LPDD

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

13.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human TCL1A Protein

SDS-PAGE: Recombinant Human TCL1A Protein [NBP1-30239]

SDS-Page: Recombinant Human TCL1A Protein [NBP1-30239] - TCL1A,13.4 kDa (114aa), confirmed by MALDI-TOF with a purity of 90% by SDS - PAGE

Formulation, Preparation, and Storage

NBP1-30239

Formulation	PBS (pH 7.4)
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TCL1A

TCL1A, also known as T-cell leukemia/lymphoma 1A, is a protein with a suggested role in intracellular regulation of T cell signaling. TCL1A binds to the pleckstrin homology domain of Akt (protein kinase B) family proteins, which facilitates Akt dimerization and activity. By increasing Akt activity TCL1A may enhance the serine/threonine phosphorylation of major Akt signaling substrates, such as Ikk complex, mTOR, BAD, p70S6 kinase, FOXO transcription factors, and GSK3b. These substrates regulate cellular differentiation, growth, survival, and metabolism. Recombinant TCL1A protein was expressed in E.coli and purified by using conventional chromatography techniques

Long Name

T Cell Leukemia Protein 1A

Alternate Names

TCL1-PEN

Gene Symbol

TCL1A

Additional TCL1A Products

Product Documents for Recombinant Human TCL1A Protein

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Product Specific Notices for Recombinant Human TCL1A Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

Cancer Biomarkers

Citations for Recombinant Human TCL1A Protein

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Recombinant Human TCL1A Protein

Novus Biologicals | Catalog # NBP1-30239

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