TCPOBOP

Catalog # Availability Size / Price Qty
1225/10
1225/50
Cat.No. 1225 - TCPOBOP | C16H8Cl4N2O2 | CAS No. 76150-91-9
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Description: Constitutive androstane receptor agonist

Chemical Name: 1,4-Bis(3,5-Dichloro-2-pyridinyloxy)benzene

Purity: ≥98%

Product Details
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Biological Activity

Agonist of the constitutive androstane receptor (CAR) (EC50 = 20 nM). Induces activity of ER1 cytochrome P450 isozymes, NADPH-cytochrome c reductase, microsomal epoxide hydrolase and glutathione S transferase. Potent mitogen; induces liver cell proliferation in mice.

Technical Data

M.Wt:
402.06
Formula:
C16H8Cl4N2O2
Solubility:
Soluble to 10 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
76150-91-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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