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2 results for "VDR-like Receptor Agonists" in Products
VDR-like Receptor Agonists
Vitamin D receptors (VDRs) are members of the NR1I family, which also includes pregnane X receptors (PXR) and constitutive androstane receptors (CAR). They form heterodimers with members of the retinoid X receptor family. VDR is expressed in the intestine, thyroid and kidney.
VDRs repress expression of 1α-hydroxylase (the proximal activator of 1,25(OH)2D3) and induce expression of the 1,25(OH)2D3 inactivating enzyme CYP24. Also, it has recently been identified as an additional bile acid ...
Vitamin D receptor (VDR) agonist
| Alternate Names: | 1,25-Dihydroxyvitamin D3 |
| Chemical Name: | (1α,3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol |
| Purity: | ≥98% |
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Selective CAR agonist
| Chemical Name: | 6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde-O-(3,4-dichlorobenzyl)oxime |
| Purity: | ≥98% |
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