TCR V beta 10 Antibody (G101) - BSA Free

Novus Biologicals | Catalog # NB100-64281

Novus Biologicals
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Key Product Details

Species Reactivity

Rat

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # G101

Format

BSA Free
View all TCR V beta 10 Primary Antibodies »

Product Specifications

Immunogen

T cell clone expressing the TCR V beta 10 gene product

Reactivity Notes

Reacts with Rat.

Localization

Cell Membrane

Specificity

NB100-64281 is specific for the T-cell receptor V beta 10 gene product. Approximately 4.2% of unseparated LEW lymph node cells were detected by this clone. Reactivity is restricted to alpha/beta T cells, of which 6.7% labelled (1).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for TCR V beta 10 Antibody (G101) - BSA Free

Application
Recommended Usage

Flow Cytometry

1:50-1:100

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TCR V beta 10

The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.

Alternate Names

T cell receptor beta locus, T-cell antigen receptor, beta polypeptide, T-cell receptor, beta cluster, T-cell receptor, beta cluster, TCRB, TRB

Entrez Gene IDs

24820 (Rat)

Gene Symbol

TRB

Additional TCR V beta 10 Products

Product Documents for TCR V beta 10 Antibody (G101) - BSA Free

Certificate of Analysis

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Product Specific Notices for TCR V beta 10 Antibody (G101) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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