TCS 183

Catalog # Availability Size / Price Qty
2236/1
TCS 183
1 Image
Description: Fragment 1-13 of GSK-3β sequence
Product Details
Citations (2)
Supplemental Products
Reviews (1)

Biological Activity

Fragment 1-13 of human and mouse GSK-3β sequence. Potentially useful as a competitive inhibitor of GSK-3β (Ser9) phosphorylation.

Control Peptide also available.

Technical Data

M.Wt:
1425.58
Formula:
C58H96N20O20S
Sequence:
MSGRPRTTSFAES

(Modifications: Ser-13 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Background References

  1. GSK3β mediates a novel interaction between LTP and LTD in the hippocampus.
    Peineau et al.
    Neuron, 2007;53:703

Product Datasheets

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for TCS 183

The citations listed below are publications that use Tocris products. Selected citations for TCS 183 include:

2 Citations: Showing 1 - 2

FAQs

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Tocris Peptides

TCS 184

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TCS-183 efficiently blocks Wnt/ beta-catenin pathway in vivo
By Jessica Vargas on 01/06/2018
Species: Mouse

TCS-183, a competitive inhibitor of the inactivating GSK-3 beta phosphorylation, was used to block the activation of Wnt/ beta-catenin pathway in vivo. 300 micro-Molar of TCS-183 was diluted in sterile artificial cerebrospinal fluid and 0.01% DMSO. Chronic intracerebral delivery of the product was achieved via an osmotic mini-pump implanted on C57BL/6 mice.

PMID: 24501359

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.