TCS 359

Catalog # Availability Size / Price Qty
2591/10
2591/50
TCS 359 | CAS No. 301305-73-7 | Flt-3 Inhibitors
1 Image
Description: Potent FLT3 inhibitor

Chemical Name: 2-[(3,4-Dimethoxybenzoyl)amino]-4,5,6,7-benzo[b]thiophene-3-carboxamide

Purity: ≥99%

Product Details
Supplemental Products
Reviews

Biological Activity

Potent inhibitor of FLT3 receptor tyrosine kinase (IC50 = 42 nM) that displays selectivity over a range of other kinases. Exhibits antiproliferative effects on MV4-11 cells, a human acute myelogenous leukemia cell line expressing a constitutively active mutant FLT3 (IC50 = 340 nM).

Technical Data

M.Wt:
360.43
Formula:
C18H20N2O4S
Solubility:
Soluble to 30 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
301305-73-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3.
    Patch et al.
    Bioorg.Med.Chem.Lett., 2006;16:3282

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for TCS 359

There are currently no reviews for this product. Be the first to review TCS 359 and earn rewards!

Have you used TCS 359?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.